目的 探讨痰热清联合更昔洛韦治疗小儿呼吸道合胞病毒性肺炎的疗效.方法 选取2012年8月至2015年12月期间收治的小儿呼吸道合胞病毒性肺炎患儿90例,采用随机数字表法随机分为观察组和对照组,2组各45例.对照组给予常规抗感染、祛痰、平喘、退热、雾化吸入等对症支持治疗,在此基础上再采用更昔洛韦注射液;观察组在对照组的基础上再联合痰热清来进行治疗.比较2组疗效、肺部啰音、咳嗽、喘息消失时间、住院时间及不良反应发生率.结果 经治疗后,观察组(93.3％)患者的总有效率显著高于对照组(75.6％),差异有统计学意义(P＜0.05);观察组患者肺部啰音(5.58± 1.41)d、咳嗽(5.78±1.61)d、喘息(3.45±0.87)d消失时间以及住院时间(5.34±0.61)d显著短于对照组(6.93±1.61、7.73±1.65、4.79±1.02、7.36±0.52),差异有统计学意义(P＜0.05);观察组(20.0％)患者的不良反应发生率与对照组(22.2％)比较,差异无统计学意义(P＞0.05).结论 痰热清联合更昔洛韦治疗小儿呼吸道合胞病毒性肺炎具有良好的疗效,不良反应少,值得临床进一步研究和应用.%Objective To evaluate the clinical efficacy of Tanreqing injection combined with ganciclovir in the treatment of pediatric respiratory syncytial virus pneumonia.Methods Ninety cases of children with respiratory tract virus pneumonia were selected in our hospital from August 2014 to December 2015,and were randomly divided into observation group and control group,and 45 cases in each group.The control group was given conventional anti infection,expectorant and antiasthmatic,antipyretic,atomization inhalation symptomatic and supportive treatment,on this basis the ganciclovir injection;the observation group was additionally given Tanreqing treatment on the basis of the control group.Then we compared the effects of two groups,pulmonary rales,wheezing,cough disappeared time,hospitalization time and the incidence of adverse reactions.Results After the treatment,the total efficiency of the observation group (93.3％) was significantly higher than that of control group (75.6％),the difference was statistically significant (P ＜ 0.05).The pulmonary rales (5.58 + 1.41),cough (5.78 + 1.61),wheezing (3.45 + 0.87) disappear time and hospital stay time (5.34 ± + 0.61) of patients in the observation group was significantly shorter than that of the control group (6.93 + 1.61,7.73 + 1.65,479 + 1.02,736,0.52),and the difference was statistically significant (P ＜ 0.05).The adverse reaction incidence in the observation group (20.0％) and the control group (22.2％) had no statistically significant difference (P ＞ 0.05) Conclusion Tanreqing injection combined with ganciclovir in the treatment of children with respiratory syncytial virus pneumonia has good efficacy and less adverse reactions,it is worthy of further research and application in clinic.
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