慢性心功能不全住院患者治疗前后肺功能的改变

摘要

目的:探索慢性心功能不全患者治疗前后肺功能的变化.方法:选取临床诊断的慢性心功能不全患者49例,于治疗前后分别进行肺通气功能、肺弥散功能及超声心动图检查,分析治疗前后各项肺功能及心功能参数的变化.结果:81.63％的慢性心功能不全患者存在限制性或混合性通气功能障碍,治疗后多项肺功能指标如1 s用力呼气容积( FEV1)、FEV1占预计值％、用力肺活量(FVC)、FVC占预计值％、最大呼气中期流量(MMEF)、一氧化碳弥散量( DLCO)均显著改善(P＜0.05),治疗后FEV1、FVC、MMEF及DLCO较治疗前分别提高6.5％、9.9％、22％和11.5％.超声心动图测出左室射血分数(LVEF)显著改善(P＜0.05).结论:慢性心功能不全患者治疗后肺通气及肺弥散功能显著改善.%Aim: This study investigates the effects of congestive heart failure on pulmonary function and assesses the Changes in pulmonary function as the Chronic Heart Failure after was treated. Methods: 49 patients with chronic systolic heart failure were included. Patients had spirometry, diffusing capacity measurements and echocardiography before and after treatment for the chronic heart failure. Results-. A restrictive ventilatory defect was present in 81. 63 percent of the patients with systolic heart failure presence. The lung function parameters such as FEV1 ,FVC,FEVl%pre,FVC%pre,MMEF and DLCO were significant increased in the patients with systolic heart failure after treatment (P＜0. 05). The mean FEV1, FVC, MMEF and DLCO improved 6. 5% ,9. 9% ,22% and 11. 5% respectively. Conclusion: Patients with systolic heart failure significant improve in lung function after treatment. Spirometry and diffusing capacity measurements can be used to assess in therapeutic effect of the congestive heart failure.