吉林省农村地区居民硒摄入量与高血压的相关性

摘要

目的：了解吉林省农村地区居民高血压患病率及矿物质硒的摄入量，探讨两者之间的关系，为高血压防治提供科学依据。方法：2005-2011年采取整群随机抽样方式抽取了吉林省部分农村地区居民1380人进行膳食调查、体格检查及生物样品检测。计算后的硒摄入量经能量校正按照三分位数分为3组，经多因素Logistic回归调整其他因素后，以第1组为参照估计其余2组发生高血压的危险。结果：吉林省农村地区居民高血压患病率为37.4％，硒的平均摄入量为35.908μg·d-1，低于中国营养学会规定的硒的推荐摄入量。校正其他危险因素后，男性硒摄入量与高血压发病呈显著负相关关系，比值比（OR）值为：1.00、0.471（95％CI 0.290-0.765）、0.596（95％CI 0.373-0.951），P值分别为0.002、0.030。女性硒摄入量与高血压发病无相关性（P＞0.05），汉族与朝鲜族人群硒摄入量与高血压发病亦无相关性（P＞0.05）。结论：硒摄入量是吉林省农村地区成年男性高血压发病的影响因素，提示增加膳食中硒的摄入对于预防男性高血压具有重要意义。%Objective To understand the prevalence of hypertension and selenium intake of the residents in rural areas of Jilin province,and to discuss the relationship between selenium intake and the prevalence of hypertension, and to provide reference for prevention and therapy of hypertension.Methods A total of 1 380 inhabitants in rural areas of Jilin province were selected by way of cluster sampling to conduct dietary investigation,physical and blood examination.The selenium intake was categorized into three groups according to tritiles after adjusted by energy, and the relative risk for incidence of hypertension in each group was estimate by using the Logistic regression model with the first group as the reference.Results The prevalence of hypertension in the study area was 37.4%.The average for selenium intake was 35.908μg·d-1 and was lower than the standard level of selenium recommended by RNI.After adjustment for other risk factors,the relative risk for incidence of hypertension for different selenium intakes in the men was 1.00,0.471(95%CI 0.290-0.765),and 0.596(95%CI 0.373-0.951),the P values were 0.002 and 0.030. There was no significant relationship between selenium intake and the incidence of hypertension in the women,and there was also no significant relationship between Han people and Korean people in China.Conclusion The selenium intake is the influencing factor affecting the incidence of hypertension of the male rural residents in Jilin province,which reminds that the increasing selenium intake is helpful for the prevention of male hypertension.