NF-κB信号传导通路在乳酸菌免疫调节中的作用

摘要

The nuclear factor-tcB (NF-kB) of the transcription factor is involved in the immune response, inflammation, and a variety of other pathological processes. Lactic acid bacteria is a human probiotic which has a lot of probiotic functions but no side effects. This article mainly discussed lactobacillus and secretions biological functions by regulating NF-kB signaling pathway. It also reviewed the ways to regulate NF-kB signaling pathway to achieve their respective biological functions.%转录因子核因子-κB(NF-κB)参与了免疫反应、炎症和其他多种病理过程.乳酸菌是人类的益生菌,无副作用,具有较多的益生功能,文中主要综述了通过乳酸菌及分泌物调节NF-κB等关键信号途径对宿主产生重要的生理作用,以及如何通过调节NF-κB信号传导通路来实现其相应的生物学功能.