微波辐射防护药物的研究进展

摘要

微波辐射可致机体发生氧化应激,使氧化产物增多和抗氧化酶活性降低,甚至引起机体组织病理学改变.药物防护可以减轻微波辐射导致的氧化应激损伤,并对微波辐射所致组织病理学改变有所改善.近年来研究的抗微波辐射药物主要有卡尼汀、褪黑激素、咖啡酸苯乙酯、绿茶及其提取物、银杏叶提取物、阿的平,以及中成药芩丹扶正胶囊和安多霖等.本文综述了微波辐射对机体的氧化损伤机制,以及微波辐射防护药物的研究现状.%Microwave radiation can lead to oxidative stress, which may increase oxidation products, reduce activity of antioxi-dant enzymes and even cause pathological changes. Protectants against microwave irradiation can reverse these injuries and alleviate the pathological changes, which include carnitine, melatonin, caffeic acid phenethyl ester, green tea and its extract, Ginkgo biloba extract, quinacrine, and traditional Chinese formulae such as Qindanfuzheng and Anduolin, etc. In this paper, the mechanism of oxidative injury induced by microwave radiation and research progress in protectants are reviewed.