目的：探讨年龄相关性黄斑变性（AMD）黄斑区的黄斑部神经纤维层(MNFL)、视网膜神经上皮层（RNL）、黄斑部视网膜脉络膜毛细血管复合体（CBRC）厚度与中医证型之间的关系。方法对确诊为AMD的126例（152只眼）患者，行光学相干断层扫描（OCT）的黄斑扫描检查黄斑区的MNFL、RNL、CBRC厚度。结果黄斑部平均MNFL厚度及各方向MNFL厚度、RNL 厚度在B1-B5区域内的、CBRC 厚度阴虚火旺型与痰瘀互结型的厚度均较脾虚湿困型及肝肾不足型厚（P<0.05），而B6-B9区域内的黄斑厚度4组间差异无统计学意义（P>0.05），痰瘀互结型与阴虚火旺型之间差异无统计学意义（P>0.05），脾虚湿困型和肝肾不足型之间的差异无统计学意义（P>0.05）。结论 AMD 患者中阴虚火旺型和痰瘀互结型的 MNFL、RNL、CBRC厚度值均高于脾虚湿困型和肝肾不足型。%Objective To explore the relations of age -related macular degeneration (AMD) macular thickness including macular neuroepithelial fiber layer (MNFL), retinal neuroepithelial layer (RNL), choriocapillario-Bruch's membrane-retinal pigment epithelium complex (CBRC) in the different TCM syndrome types. Methods A clinical study records of 126 AMD patients (152 eyes) were divided into four groups based on TCM syndrome type. The thicness of MNFL, RNL and CBRC in macular region are scaned by optical coherence tomography (OCT). Results The MNFL thickness of various syndrome, the thickness of RNL in the B1-B5 region, the CBRC thickness of fire excess from Yin deficiency type and phlegm and blood stasis are increased than the spleen deficiency and dampness type and deficiency of liver and kidney type thickness (P<0.05);there was no significant difference between the four groups in the macular thickness in the B6-B9 region (P>0.05);there was no significant difference between the phlegm and blood stasis type and fire excess from yin deficiency type (P>0.05); there was no significant difference between the Spleen deficiency and dampness type and deficiency of liver and kidney type (P>0.05). Conclusion The thickness of MNRL, RNL and CRBC of AMD patients of fire excess from Yin deficiency type and phlegm and blood stasis are higher than the spleen deficiency and dampness type and deficiency of liver and kidney type.
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