超声剪切波弹性成像与核素SPECT显像对甲状腺癌诊断的对比研究

摘要

ABSTRACT:Objective To compare the diagnostic value of shear wave elastography and single-photon emission computed tomography (SPECT)99m TcO4 - imaging in thyroid cancer. Methods All 148 thyroid nodules as research subjects were checked by shear wave elastography and radionuclide SPECT imaging,based by the pathology as the gold standard,two methods for calculating the diagnosis of thyroid cancer sensitivity,specificity,accuracy,positive predictive value and negative predictive value were compared.Results All of the 148 thyroid nodules,there were 39 malignant nodules (26.35%),109 benign nodules (73.65%).About the sensitivity, specificity,accuracy,positive predictive value and negative predictive value,shear wave elastography in the diagnosis of thyroid cancer in a variety of indicators were higher than SPECT 99m TcO4 - imaging.Conclusion Shear wave elastography in the diagnosis of thyroid cancer is higher than radionuclide SPECT 99m TcO4 - imaging,and shear wave elastography should be preferred for first clinical use.The combination of the two methods will increase the value in the diagnosis of thyroid carcinoma.%目的：比较超声剪切波弹性成像与单光子发射型计算机断层摄影（single-photon emission computed tomography，SPECT）高锝酸盐（99m TcO4－）显像2种检查方法对甲状腺癌的诊断价值。方法148个甲状腺结节均行超声剪切波弹性成像及核素 SPECT 99m TcO4－显像，以病理为金标准，计算2种方法诊断甲状腺癌的灵敏度、特异度、准确度、阳性预测值及阴性预测值。结果病理诊断148个甲状腺结节中，恶性结节39个（26．35％），良性结节109个（73．65％）。超声剪切波弹性成像诊断甲状腺癌的灵敏度、特异度、准确度、阳性预测值及阴性预测值均高于 SPECT 99m TcO4－显像。结论超声剪切波弹性成像对甲状腺癌的诊断价值高于核素 SPECT 99m TcO4－显像，在临床应用中应以超声为首选，将两者结合综合应用将提高对甲状腺癌的诊断价值。