调Q开关Nd:YAG1064nm激光联合逍遥丸加减治疗黄褐斑效果的临床研究

摘要

目的 探讨调Q开关Nd:YAG 1 064 nm激光联合逍遥丸加减治疗黄褐斑的临床疗效及安全性.方法 将黄褐斑患者40例随机分成治疗组和对照组各20例,治疗组给予调Q开关Nd:YAG 1 064 nm激光联合逍遥丸加减治疗,对照组给予调Q开关Nd:YAG 1 064 nm激光治疗.每次治疗前后应用皮肤测量仪检测皮肤黑素指数、红斑指数、皱纹指数.结果 治疗后2组黑素指数、红斑指数、皱纹指数均呈逐渐降低趋势,治疗组低于对照组,组间、不同时点间和组间·不同时点间交互作用差异均有统计学意义(P<0.05).结论 调Q开关Nd:YAG 1 064 nm激光联合逍遥丸加减治疗黄褐斑效果显著,安全且不易复发.%Objective To discuss the clinical efficacy and safely of the Q-switched 1 064 nm laser combined with free and Xiaoyao Pill in the treatment of chloasma.Methods Forty cases patients with chloasma were randomly divided into two groups.The treatment group(20 cases) was given Q-switched 1 064 nm laser combined with free and Xiaoyao Pill treatment.The control group(20 cases) was given a simple Q-switched 1 064 nm laser treatment.The skin melanin/erythema/wrinkle index were measured with a skin evaluation instrument before and after each treatment.Results After treatment,2 groups of melanin index,erythema index,wrinkle index decreased gradually.The treatment group was lower than the control group.There was significant difference in interaction between different groups,different time points and between different time points of groups(P<0.05).Conclusion The Q-switched 1 064 nm laser combined with free and Xiaoyao Pill on chloasma is a safe and effective and not easy to relapse.