1470nm半导体激光汽化术与经尿道前列腺电切术后的炎症及应激反应程度比较

摘要

Objective:To investigate the differences in inflammatory response and stress response after 1470nm semi-conductor laser vaporization and transurethral resection of the prostate(TURP).Results:220 patients with prostatic hyperpla-sia who underwent surgical treatment in Handan Central Hospital between January 2016 and May 2017 were reviewed and di-vided into the TURP group(n=130)who received TURP therapy and laser group(n=90)who received who received 1470nm semiconductor laser vaporization.The differences in serum levels of inflammatory mediators and stress hormones were com-pared between the two groups before operation and 24h after operation.Results:Before operation,there was no statistically sig-nificant difference in serum levels of inflammatory mediators and stress hormones between the two groups(P>0.05).24h af-ter operation,serum inflammatory mediators IL-1β,IL-2,IL-6,IL-4,IL-10 and IL-13 levels were lower than those of TURP group;serum stress hormones Cor,NE and E levels were lower than those of TURP group.Conclusion:1470nm semiconduc-tor laser vaporization for patients with prostatic hyperplasia causes less inflammatory response and stress response than TURP, and is minimally invasive.%目的:探讨1470 nm半导体激光汽化术与经尿道前列腺电切术(T U RP)后的炎症及应激反应程度差异.结果:选择在本院接受手术治疗的220例前列腺增生患者,回顾治疗方案并将其分为接受T U RP治疗的T U RP组130例、接受1470 nm半导体激光汽化术治疗的激光组90例.对比两组患者术前及术后24 h时血清中炎症介质、应激激素含量的差异.结果:术前,两组血清中炎症介质、应激激素含量的差异无统计学意义(P>0.05).术后24 h,激光组血清中炎症介质IL-1β、IL-2、IL-6、IL-4、IL-10、IL-13的含量低于TURP组;血清中应激激素Cor、NE、E的含量低于TURP组.结论:前列腺增生患者接受1470 nm半导体激光汽化术治疗,较T U RP所致炎症及应激反应轻,具有微创优势.