健脾和胃降逆止呕中药内服加穴位贴敷治疗妊娠恶阻脾胃虚弱证的临床研究

摘要

【目的】观察健脾和胃降逆止呕中药穴位贴敷治疗妊娠恶阻的临床疗效。【方法】将122例妊娠恶阻脾胃虚弱证患者随机分为观察组63例和对照组59例，对照组2例中途退出，最终纳入57例。对照组采用健脾和胃降逆止呕中药内服、静脉输液、饮食起居护理与情志调护，观察组在对照组治疗的基础上加用健脾和胃降逆止呕中药穴位贴敷。每日1次，4d为1个疗程，连续治疗2个疗程。观察2组妊娠恶阻临床症状的改善情况，比较2组临床疗效，并评价其安全性。【结果】（1）观察组总有效率为96.8%，显著优于对照组的71.9%（P＜0.01）；（2）观察组呕吐症状消失所需时间显著少于对照组（P＜0.01）；（3）治疗过程中，2组均无明显不良反应情况发生。【结论】健脾和胃降逆止呕中药穴位贴敷可显著提高妊娠恶阻的临床疗效，联合中药内服、静脉输液、饮食起居护理与情志调护可达最佳治疗效果。%Objective To observe the clinical effect of oral use and acupoint application of Chinese herbal medicine with the actions of strengthening spleen and regulating stomach, lowering rebellious Qi to stop vomiting in treating pregnant pernicious vomiting. Methods One hundred and twenty-two spleen-stomach deficiency pregnant pernicious vomiting cases were randomly divided into observation group ( N=63) and control group (N=59). At the end of the trial, 2 cases of the control group dropped out, and the total case number was 57 in the control group. Both groups were treated with intravenous infusion, dietary care, daily life and emotional nursing, and oral use of Chinese herbal medicine with the actions of strengthening spleen and regulating stomach, lowering rebellious Qi to stop vomiting. Additionally, the observation group was given acupoint application of herbs for strengthening spleen and regulating stomach, lowering rebellious Qi to stop vomiting. The treatment was performed once a day, 4 days constituted one treatment course, and the treatment lasted two continuous courses. The improvement of vomiting, therapeutic effect and the safety were compared between the two groups after treatment. Results ( 1) The total effective rate was 96.8%in the observation group and was 71.9%in the control group, the difference being significant (P<0.01). (2) The time for stopping vomiting in the observation group was significantly less than that in control group (P<0.01). (3) During the treatment, no obvious adverse reaction was found in the two groups. Conclusion Acupoint application of herbs for strengthening spleen and regulating stomach, lowering rebellious Qi to stop vomiting has obvious synergistic effect on the clinical efficiency of spleen-stomach deficiency pregnant pernicious vomiting treated by oral use of herbal medicine, intravenous infusion, dietary care, and daily life and emotional nursing.