舍尼通治疗合并前列腺炎的BPH患者术后下尿路症状的临床研究

摘要

目的:评估舍尼通治疗合并组织学前列腺炎的良性前列腺增生(BPH)患者前列腺电切术(TURP)术后仍存在的下尿路症状的疗效.方法:将接受经尿道前列腺电切术,术后病理诊断证实BPH并合并组织学前列腺炎的180例患者随机分为两组,其中A组:空白对照组90例,B组:舍尼通治疗组90例.用IPSS评分系统评估各组术后第1个月及治疗1个月后的下尿路症状.结果:A组观察1个月后和B组舍尼通治疗1个月后的IPSS评分分别为(12.04±4.73)分和(6.56±2.84)分,差异有统计学意义(P＜0.001).A组有效率2.2％,B组有效率91.1％.结论:舍尼通能明显改善合并组织学炎症的BPH患者手术后仍存在的下尿路症状,且无药物不良反应.%Objective:To evaluate the efficacy of prostat in the treatment of lower urinary tract symptoms (LUTS) in the postoperative patients of benign prostatic hyperplasia (BPH) with histological prostatitis.Methods:A total of 180 patients diagnosed of BPH with histological prostatitis by pathological diagnosis after transurethral resection of prostate (TURP) were enrolled in the trial.The cases was randomly divided into control group (n =90) and prostat treatment group B (n =90).The LUTS of each group was evaluated by IPSS scoring system in the first month and the second month after the TURP.Results:After observation of one month,the IPSS scores of control group were 12.04±4.73.The IPSS scores of treatment group were 6.56±2.84 after one month treatment by prostat.The difference was statistically significant (P＜0.001).The effective rate was 2.2％ and 91.1％ respectively.Conclusion:Prostat is effective and safe in relieving the LUTS in the postoperative patients of BPH with histological prostatitis.