抗CD20单克隆抗体治疗老年弥漫性B细胞淋巴瘤的研究

摘要

目的：观察抗CD20单克隆抗体治疗老年弥漫性B细胞淋巴瘤的临床疗效。方法：将我院收治的老年B细胞淋巴瘤28例分为两组，一组为R-CHOP组15例，另一组为对照组CHOP组，4-6个疗程进行疗效评价。结果：RCHOP方案组总缓解率为73.3.%，对照组CHOP方案治疗总缓解率为46.2%，不良反应与对照组无明显增加。结论：抗CD20单克隆抗体联合化疗治疗老年B细胞淋巴瘤疗效好，不良反应少。%Objective:To observe the anti CD20 monoclonal antibody the clinical curative effect of the treatment of senile diffuse B cel lymphoma,Method:The aged B cel lymphoma in our hospital 28 cases were divided into two groups,A group of 15 patients in the R-CHOP group,Another group was control group CHOP group,To evaluate the curative effect of 4-6 Results: the RCHOP regimen group total remission rate was 73.3.%,The control group of CHOP regimen in the treatment of the total response rate was 46.2%,Adverse reactions and control group had no obvious increase.Conclusion: Anti CD20 monoclonal antibody combined with chemotherapy efficacy in the treatment of aged B cel lymphoma, less adverse reaction.