宏基因组学在法医学鉴定中的应用

摘要

随着分子生物学与基因组学的发展,宏基因组学在法医学与法医学鉴定中逐渐扮演着重要的角色.近年来,宏基因组学作为研究环境微生物菌群构成与多样性、各成员之间相互关系及与环境之间相互关系的分支学科,在法医学鉴定相关领域的应用也逐渐兴起,并带来了新的契机.本文对宏基因组学研究策略及其在法医学鉴定中个体识别、案发现场生物斑迹来源鉴定及药物滥用检测等方面的应用现状进行了综述,旨在进一步阐明宏基因组学在法医学中的作用与应用价值.%With the development of molecular biology and genomics,metagenomics is playing a more important role in forensic science and forensic identification.In recent years,as a branch discipline studying the composition profile and diversity of microbe flora as well as studying the interaction within microbe and with environment,the application of metagenomics has gradually risen and brought new opportunities for forensic identification-related area.In this review,strategy of metagenomics and its application in forensic identification including individual identification,origin determination of biological stain in crime scene and drug abuse detection are summarized.This article aims to elucidate the role and application value of metagenomics in forensic science.