In vivo therapeutic effect of in situ injection of recombinant adenovirus expressing mIFN-y gene on glioblastoma

摘要

Patients with malignant glioma have a poorprognosis despite the combined use of surgery,irradiation, chemotherapy, and a variety ofimmunotherapies. These patient are known to showdecreased circulatory immune function and suppression ofthe tumor-specific immune response. Interferon-γ(IFN-