Objective To investigate the urodynamic changes of female bladder outlet obstruction ( FBOO) and the clinical diagnosis and prognosis value of urodynamic examination.Methods Thirty-two female outpatients with mean age of 56.3 (21 to 80 years) were suspecious with FBOO according to their clinical presentations.Their chief complaints included low urinary tract symptoms such as frequent micturition,urgent urination and dysuria.All patients received cystoscopy and cys-tourethrography examination.Urodynamic examination was also performed in all patients.Patients with confirmed diagnosis of anatomical FBOO received Transurethral Resection of Bladder Neck.Urinary ultrasonography and dynamic examination were performed and compared again after 3 months of the operation.Results Twenty cases were confirmed with diagnosis of anatomical FBOO,7 cases with functional FBOO, and 5 normal cases.Compared to functional FBOO group, anatomical FBOO group showed significant urodynamic changes including Qmax,Pdet.Qmax,Pdet.max and MUCP (P<0.05).For the 20 cases received operation,significant differences were seen in Qmax,Pdet.Qmax,Pdet.max,MUCP and RV before and after operation (P<0.05).Conclusions The confirmed diagnosis of functional bladder and obstructive disease of the bladder neck could be made by urodynamic examination.It's safe and efficient and has fewer complications in TURBN. Urodynamic examination plays an important role in the follow-up of female FBOO patients.%目的：探讨尿动力学检查在女性膀胱出口梗阻（ FBOO）的诊治及尿动力学检查的应用价值。方法收集32例疑似FBOO的患者，年龄21～80岁，平均56．3岁。主诉有尿频、尿急、排尿困难等下尿路症状，对患者完善常规检查，同期行膀胱镜、排尿期尿道造影以及尿动力学检查。对确诊为解剖性FBOO的患者行经尿道膀胱颈切开术，术后3个月进行随访比较。结果32例疑似FBOO患者中解剖性FBOO20例，功能性FBOO7例，正常5例。解剖性FBOO组与功能性FBOO组比较尿动力指标，其中最大尿流率、峰值尿流率膀胱逼尿肌压力、最大逼尿肌压力、最大尿道闭合压差异均有显著性意义（ P＜0．05）。对20例解剖性FBOO患者行经尿道膀胱颈切开术，术后3个月进行随访。术前和术后比较，最大尿流率、峰值尿流率膀胱逼尿肌压力、最大逼尿肌压力、最大尿道闭合压、残余尿量差异均有显著性意义（P＜0．05）。结论尿动力学检查可对功能性与解剖性的女性膀胱出口梗阻作出客观判断。经尿道离子束刀膀胱颈切开术治疗解剖性FB00疗效安全、恢复快、并发症少。尿动力学检查在女性膀胱出口梗阻术后评价方面具有重要价值。
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