维持性血液透析患者并发 Wernicke 脑病12例临床分析

摘要

Objective:To investigate the clinical characteristics and treatments of patients with maintenance hemodial -ysis complicating Wernicke encephalopathy .Methods:Clinical data of 12 cases with maintenance hemodialysis complicating Wernicke encephalopathy were analyzed retrospectively .Results: The clinical manifestations of maintenance hemodialysis complicating Wernicke's encephalopathy are typical , and vitamin B 1 showed a good therapeutic effect .Ten cases cured , 1 case died of lung infection caused by repeated convulsion , 1 case with residual recent memory loss , but improved marked-ly.During the treatment, the symptom of ophthalmoplegia relieved first , followed by neuropsychiatric symptoms , and com-monly showed obvious effect in 2 days.Other symptoms recovered after a long time , needing 4~6 weeks.Conclusions:Clinical physicians should pay attention to the recognition of the disease , diagnosis and treatment , in order to improve the quality of life of the uremic survivals .%目的：探讨维持性血液透析患者并发Wernicke 脑病的临床特点及治疗方法。方法：回顾性分析12例维持性血液透析并发Wernicke脑病患者的临床资料。结果：维持性血液透析患者并发Wernicke脑病时临床表现不典型，维生素B1治疗效果好。12例患者中1例因反复抽搐致肺部感染死亡，10例治愈，1例仍表现为近记忆缺失，但较入院时明显好转。治疗中眼肌麻痹最先缓解，其次为神经精神症状，一般治疗2d可见明显效果。其他症状恢复时间较长，需4～6周。结论：临床医师应重视对该病的认识、诊断与治疗，提高尿毒症患者的生存质量。