Objective To comprehend the prevalence of colorectal cancer in SongZi city,HuBei province, and explore the method of the screening program for colorectal cancer. Methods Adopt the random cluster and stratified sampling, at the 14 screening sites, 23 157 residents were recruited as target population. And these residents aged over 40 years old, they were accepted the quantity risk evaluation questionnaire and SFOBT. Those with positive SFOBT underwent colonoscopy. Results It was supposed have 21 753 residents for this screening program. Actually, only have 4 452 residents join this program, there are 172 people of them is positive, 63(36. 6%) participants underwent colonoscopy. 47(74. 6%) residents were pathological changes, and colorectal cancer was found in 3 case{6. 38%) , colorectal adenoma in 14 case (29. 8%) , ulcerative colitis in 2 case(4. 25%), proctitis in 16 case{34%) , hemorrhoid and fistula and another anus disease in 12 case (25. 5%). Conclusion The prevalence of colorectal cancer for these people whose aged over 40 year old in Songzi city,HuBei province, and the case rate is 67. 39/10 thousand, the SFOBT and the quantity risk evaluation investigation is available and feasible in screening early changes of colorectal cancer.%目的 了解湖北松滋地区结直肠癌的患病率,探讨结直肠癌筛查的方法.方法 采取整体分层随机抽样,选取14个筛查点40周岁以上人群共23157人为筛查对象进行数量化风险评估问卷调查和SFOBT检查,阳性者进行结肠镜检查.结果 应参加筛查21753人,实际参加初筛4452人(20.5%),阳性172人,接受结肠镜检查63人(36.6%),检出有病变者47人(74.6%),其中结直肠癌3例(6.38%)、结直肠腺瘤14例(29.8%)、溃疡性结肠炎2例(4.25%)、直肠炎16例(34%)、痔瘘及其他肛门疾病12例(25.5%).结论 湖北松滋地区40周岁以上结直肠癌患病率为67.39/10万,数量化风险评估问卷调查和序贯法粪隐血筛检试验结合结肠镜检查能够有效的从目标人群中检出早期结直肠癌和癌前病变.
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