结肠癌术后不同时机肠内营养对机体胃肠功能和营养状况的影响

摘要

Objective To study the effect of different timing of enteral nutrition on gastrointestinal function after colon cancer operation.Methods A total of 70 patients undergoing radical operation of colon cancer were randomly divided into two groups,with 35 cases in each group.The treatment group received enteral nutrition on the 1st day after operation,while the control group received on the 3rd day.The recovery of gastrointestinal function [serum albumin (ALB),prealbumin (PA),prognostic nutritional index (PNI),anal exhaust time,defecation time and liquid diet time] and the incidence of postoperative complications were compared between groups.Results One week after operation,ALB,PA and PNI in the observation group [(37.03±3.18) g/L,(262.95±35.48) mg/L,(54.78±8.11) points] were significantly higher than those in the control group (P ＜ 0.05).The postoperative anal exhaust time and defecation recovery time of the observation group were significantly shorter than those of control group (P ＜ 0.05).The incidence rates of anastomotic fistula and renal dysfunction were significantly lower than those in control group (P ＜ 0.05).Conclusion Early enteral nutrition intervention after colon cancer operation is helpful to the recovery of gastrointestinal function,with good safety.%目的 研究结肠癌术后不同时机肠内营养对胃肠功能的影响.方法 纳入70例接受结肠癌根治术患者作为研究对象,随机分为两组,每组各35例.观察组术后第1d即开始肠内营养,对照组术后第3d开始肠内营养.比较两组干预前后机体营养状况和胃肠功能恢复情况[血清白蛋白(ALB)、前白蛋白(PA)、营养指数(PNI)、肛门排气时间、排便时间及经口进食流质时间]及术后并发症发生率.结果 观察组术后1周ALB、PA、PNI分别为(37.03±3.18) g/L、(262.95±35.48) mg/L及(54.78±8.11)分,显著高于同时点对照组(P＜0.05),观察组术后肛门首次排气时间和排便恢复时间均显著短于对照组(均P＜ 0.05),观察组术后吻合口漏和肾功能不全发生率均显著低于对照组(均P＜ 0.05).结论 结肠癌术后早期肠内营养干预有助于胃肠功能的早期恢复,改善机体营养状况,且安全性良好.