乳腺导管内乳头状瘤超声引导下麦默通治疗术后复发及原因分析

摘要

Objective To investigate the postoperative recurrence and possible causes of recurrence after treatment of intraductal papilloma(IP) of the breast with Mammotome biopsy under ultrasound guidance.Methods The clinical profiles of 104 patients with IP were retrospectively analyzed.All patients underwent Mammotome resection under ultrasound guidance and were followed up by uhrasonography to observe the curative effect,and the possible causes of recurrence were further analyzed.Results Nodules in the original location were shown in a total of 14 cases during 3～45 months(mean 35 months) follow-up.Recurrence in situ was found in 1 case on the 3th month,3 cases on the 6th month,3 cases on the 21th months,3 cases on the 33th month,4 cases on the 45th month.The number of lesions was a risk factor for recurrence of IP after Mammotome(OR=1.780,P＜0.05).The time of recurrence was not related to the age,the size of lesions,the grade of BI-RADS and the number of lesions.Conclusion The indications should be strictly controlled,although the Mammotome biopsy system is an alternative treatment of IP.It should be careful used when the preoperative diagnosis is suspected non-solitary IP.%目的 研究超声引导下麦默通治疗乳腺导管内乳头状瘤术后复发隋况,分析其复发的可能原因.方法 选取经超声引导下行麦默通治疗术切除乳腺导管内乳头状瘤患者104例,应用超声密切随访,观察疗效.术后复发者进一步分析导致复发的可能原因.结果 术后随访3～45个月(平均35个月),共有14例超声检查显示肿瘤原位有结节形成,随访至3个月原位复发1例,6个月原位复发3例,21个月原位复发3例,33个月原位复发3例,45个月原位复发4例.病灶数量是其麦默通术后复发的危险因素(OR=1.780,P＜0.05);且病灶的复发时间与患者年龄、病灶大小、病灶BI-RADS分级及病灶数量均无关.结论 麦默通微创旋切系统是治疗乳腺导管内乳头状瘤的方法之一,有复发的可能,合理选择适应证,即术前怀疑非单发性的乳头状瘤时,应慎用麦默通手术.