超声助力式弹性成像联合声触诊组织成像量化技术对BI-RADS 4类乳腺肿块的诊断价值

摘要

目的 探讨超声助力式弹性成像联合声触诊组织成像量化(VTQ)技术对BI-RADS 4类乳腺肿块的诊断价值.方法 选取经病理确诊且经二维超声诊断为BI-RADS 4类的乳腺肿块患者95例(共97个肿块),均行助力式弹性成像和VTQ检查,以病理结果为金标准,绘制二维超声、助力式弹性成像联合VTQ检查诊断乳腺肿块的ROC曲线,比较其诊断效能;比较助力式弹性成像联合VTQ技术与二维超声对乳腺肿块BI-RADS分类的差异.结果 二维超声对乳腺肿块的诊断敏感性、特异性、准确率、阳性预测值、阴性预测值及曲线下面积分别为87.80％、53.57％、41.38％、58.06％、85.71％及0.703,助力式弹性成像联合VTQ技术调整BI-RADS分类后的诊断敏感性、特异性、准确率、阳性预测值、阴性预测值及曲线下面积分别为95.12％、83.93％、79.05％、81.25％、95.92％及0.895,差异均有统计学意义(均P＜0.05).结论 超声助力式弹性成像联合VTQ技术可提高对BI-RADS 4类乳腺肿块的诊断价值.%Objective To explore the value of ultrasound elastography combined with acoustic touch tissue imaging quantification (VTQ) in diagnosis of BI-RADS 4 class of breast lumps.Methods Ninety-five patients with breast lumps (a total of 97 lesions) were confirmed by pathological diagnosis of 2D ultrasound as BI-RADS 4 class were selected.Then they were examined by elastography and VTQ,pathological results used as the golden standard,the ROC curve of 2D ultrasound and elastography combined with VTQ were plotted,and the diagnostic efficiency was evaluated,the difference of diagnosis of BI-RADS of breast lumps by 2D ultrasound and elastography combined with VTQ were compared.Results The diagnostic sensitivity,specificity,accuracy,positive predictive value,negative predictive value and AUC of 2D ultrasound were 87.80％,53.57％,41.38％,58.06％,85.71％ and 0.703,respectively.While the diagnostic sensitivity,specificity,accuracy,positive predictive value,negative predictive value and AUC by elastography combined with VTQ adjusted BI-RADS classification were 95.12％,83.93％,79.05％,81.25％,95.92％ and 0.895,respectively.The differences between two methods were statisticlly significant(all P＜0.05).Conclusion Ultrasound elastography combined with VTQ could improve the diagnostic value of BI-RADS 4 class breast lumps.