Objective To investigate the possibility and the safety ofresecting large hepatocellular carcinoma.Methods 78 cases of large hepatocellular carcinoma were analyzed retrospectively and compared with 27 cases of small hepatocellular.Results The extension of resection, blood loss, operational duration and morbidity in the large hepatocellular carcinoma group were significantly greater than those in small counterpart (P<0.05). But there was no significant difference in mortality between the two groups.Conclusions It is advisable to resect large hepatocellular carcinoma actively. The hepatic resection is safe and feasible in selected patients with large hepatocellular carcinoma.%目的 探讨手术切除大肝癌的可行性和安全性。方法 回顾性分析总结我院近10年施行手术切除的78例大肝癌的资料,并与同期手术治疗的27例小肝癌进行比较。结果 大肝癌组施行的手术切除范围、术中失血量显著大于小肝癌组,手术时间亦明显长于小肝癌,因而并发症率也高(P<0.05),但两组间的死亡率并无显著差别(P>0.05)。结论 大肝癌应积极地进行手术切除。经过仔细地选择病例,手术切除是安全可行的。
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