乳腺癌循环肿瘤细胞临床应用的相关研究

摘要

乳腺恶性肿瘤的复发和转移，是乳腺癌患者的主要致死原因。如何早期发现乳腺恶性肿瘤细胞的转移并及时予以治疗，是目前研究的热点。循环肿瘤细胞（ circulating tumor cell， CTC）的发现有望为乳腺癌的诊断和治疗提供新的思路。检测 CTC 有助于早期发现肿瘤的微转移，指导个体化治疗，评价治疗效果及预后。我们对 CTC 的研究进展进行综述。%Recurrence and metastasis is the main cause of death in breast cancer patients. Early detection and treatment of malignant breast cancer cells and metastasis are the hotspots of current resear-ches. The discovery of circulating tumor cells(CTC)may provide new ideas for the diagnosis and treatment of breast cancer. Detection of CTC will help the early detection of micrometastasis,the guidance of individ-ual treatment,and the evaluation of therapeutic effect and prognosis. Domestic and foreign research pro-gress of CTC was reviewed in this paper.