C反应蛋白和血清前蛋白在老年社区获得性肺炎预后中的意义

摘要

Objective To investigate the implication of c - reactive protein and serum precursor protein in the prognosis of the old community-acquired pneumonia. Methods 109 old community-acquired pneumonia were retrospectively amdyzed with 40 non-hospitalised patients with CAP at the same period for the control group. According to prognosis ,patients were divided into improved groups( A group)and referral group( B group). The prognosis of different groups were compared by statistical analysis. The CRP and PA in serum concentration of each group was recorded at the first i day,7 days. Results Compared with the control group, the PA of the patients with CAP group reduced significantly,while CRP significantly increased, the difference was significant (P ＜ 0. 01 );In CAP patients, compared with the transferred ,the PA of improved group significantly reduced, CRP was significantly increased, the difference was significant ( P ＜ 0. 01 ).Conclusions CRP and PA dynamic monitoring for evaluating the prognosis in old CAP has an important clinical significance.%目的 探讨C-反应蛋白(CRP)及血清前白蛋白(PA)的变化对老年社区获得性肺炎(CAP)患者预后的评估作用.方法 对入住我院109名老年CAP患者进行回顾性分析,以同期住院的40名老年非CAP患者为对照组.根据预后将患者分为好转组(A组)和转院组(B组).通过统计学处理分析不同组别的预后并进行比较.分别记录各组入院第1天、第7天的CRP、和PA的血清含量.结果 CAP患者组、对照组相比较,PA明显降低,CRP则明显升高,差异有显著性(P<0.01) ;CAP患者中,好转组与转院组相比,PA明显降低,CRP则明显升高,差异有显著性(P<0.01).结论 CRP和PA动态监测对于评价老年CAP预后具有重要的临床指导意义.