Objective To observe the sedation effect of dexmedetomidine of noninvasive positive pressure ventilation ( NIPPV ) in the treatment oi AECOPD patients complicated with respiratory failure, and to review its relevant literatures. Methods 7 AECOPD patients complicated with respiratory failure, who had initially failed in NIPPV, were subsequently tranquilized by dexmedetomidine. Their blood gas analysis, vital signs and curative effect were observed. Results 6 patients had a ideal sedation after the use of dexmedetomidine and were able to cooperate with NIPPV, without major adverse reactions. 2 of them were successfully weaned from the mechanically ventilated support without intubation. Conclusion Sedative therapy for patients undergone NIPPV therapy maybe useful, and dexemedemidine maybe is a safe and effective drug for the sedative therapy of these patients.%目的 对右美托咪定用于AECOPD合并呼吸衰竭患者无创机械通气时镇静治疗,观察其疗效.方法 对7例接受无创机械通气失败的患者,使用右美托咪定对其进行镇静治疗,并观察血气分析指标、生命体征变化及最终治疗效果.结果 6名患者在接受右美托咪定镇静治疗后可达到理想镇静深度,其中2名患者最终避免了气管插管而治愈.结论 NIPPV时行镇静治疗可改善人机关系,而右美托咪定可能是一种较为安全且有效的镇静药物.
展开▼
