Objective To evaluate the antibody detection of TB - SA in the diagnosis of patients with tuberculous pleurisy. Methods 121 patients with tuberculous pleurisy and 30 patients with non-tuberculosis pleurisy were selected in this study, and the antibodies of TB-SA in their pleural fluid and serum were detected by enzyme linked immunosorbent assay ( ELISA ). Results The sensitivities of TB-SA antibody were 68. 60% in pleural fluid and 33. 38% in serum respectively in the tuberculous pleurisy group, while the sensitivities in pleural fluid and serum were 96. 67% both in the non-tuberculous pleurisy group. The sensitivity difference of TB-SA antibody between pleural fluid and serum in the tuberculous pleurisy group had statistical significance ( P ＜0. 05 ). Conclusion The antibody detection of TB-SA in pleural fluid and serum shows an acceptable sensitivity and magnificent specificity in the diagnosis of tuberculous pleu-ritis, which has a better reference value in the differential diagnosis of tuberculous pleurisy.%目的 评估胸水和血清特异性TB-SA结核抗体对结核性胸膜炎的诊断价值.方法 用TB-SA 抗体IgG检测试剂盒(酶联免疫法)分别检测121例结核性胸膜炎和30例非结核性胸膜炎胸水、血清标本中的TB-SA结核抗体,分析实验资料.结果 121例结核性胸膜炎组中,胸水检测TB-SA抗体的敏感性为68.60%,血清检测TB-SA抗体的敏感性为33.88%.30例非结核性胸膜炎组胸水检测的特异性为96.67%,血清检测特异性为96.67%.结论 胸水TB-SA抗体检测在结核性胸膜炎的诊断和鉴别诊断中具有较重要的参考价值.
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