Objective To investigate the clinical characteristics of lipid pneumonia, and to improve the un-derstanding of the disease. Methods The clinical data of 8 cases of lipid pneumonia were retrospectively analyzed. Results In the 8 patients, there were 5 males and 3 females with age from 35 to 71 years ( mean age 50. 6 years) , respectively. Most patients were diagnosed because of cough, chest pain, etc. Radiography showed a airspace consol-idations, ground-glass attenuation, airspace nodules and 'crazy-paving' pattern. Histopathology revealed lipoid pneu-monia was a chronic foreign body reaction to fat, characterized by lipid-laden macrophages. Conclusion Lipid pneumonia diagnosis relies on his-topathology. Surgical resection and prednisolone are clinical treatment for lipid pneumonia, and non-surgical treatment patients need a long-term follow-up.%目的 探讨脂质性肺炎的临床特征,提高对该疾病的认识.方法 对8例脂质性肺炎的临床特征进行回顾性分析.结果 8例患者中,男性5例,女性3例,年龄35-71岁,平均50.6岁,因咳嗽、胸痛等就诊.影像学多显示:斑片样实变、空洞病灶旁实变、结节型肿块,磨玻璃样、铺路石样改变.病理组织学显示:肺泡内聚集的载脂的巨噬细胞、空泡细胞、胆固醇结晶、慢性炎症.结论 脂质性肺炎主要依赖于病理组织形态学.泼尼松或手术切除是临床治疗脂质性肺炎必要手段,未手术患者需定期随访.
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