原发性肝癌动脉介入治疗效果及影响因素分析

摘要

Objective To investigate the factors affecting the outcome of arterial intervention for primary hepatic carcinoma .Methods T he clinical data of 184 patients w ho underwent interventional therapy for primary liver cancer w ere collected and co mpared .Analyze the factors affecting the outcome of arterial in‐terventional therapy for primary liver cancer .Results Interventional therapy was effective in 135 cases , and the total effective rate w as 73 .37% .T here w ere significant differences in maximum tumor diameter , arteriovenous fistula ,portal vein tumor thro mbus ,distant metastasis ,pseudocapsule ,Child‐Pugh classifi‐cation ,clinical stage of Barcelona liver cancer ,and num ber of interventional treatments in patients w ith different clinical data ( P＜0 .05 or 0 .01 ).T he maximum tumor diameter ,portal vein tumor throm bus , pseudocapsule ,Child‐Pugh classification ,clinical stage of Barcelona liver cancer ,and num ber of interven‐tional treatments w ere independent risk‐related factors affecting the outcome of arterial interventional ther‐apy for primary liver cancer (P＜0 .05).Conclusion T here are many factors influencing the effect of arte‐rial intervention in patients w ith primary liver cancer .Early identification of high risk factors is beneficial to minimize the risk of interventional therapy ,improve the effect of interventional therapy ,and improve the prognosis .%目的 探讨影响原发性肝癌动脉介入治疗效果的相关因素.方法 收集184例行原发性肝癌介入治疗患者的临床资料并进行比较,分析影响原发性肝癌动脉介入治疗效果的相关因素.结果 介入治疗总有效135例,总有效率为73 .37%.不同临床资料患者肿瘤最大直径、动静脉瘘、门脉瘤栓、远处转移、假包膜、Child‐Pugh分级、巴塞罗那肝癌临床分期、介入治疗次数比较差异有统计学意义( P＜0 .05或0 .01) .肿瘤最大直径、门脉瘤栓、假包膜、Child‐Pugh分级、巴塞罗那肝癌临床分期、介入治疗次数是影响原发性肝癌动脉介入治疗效果的独立危险因素(P＜0 .05) .结论 原发性肝癌患者动脉介入治疗效果的影响因素较多,早期明确高危因素,利于最大限度降低介入治疗风险,提高介入治疗效果,改善预后.