Objective To assess the study design, methodological quality and area of research in origninal articals published in the Journal of Clinical Pediatrics. Methods All original articals published from 2005 to 2012 were reviewed and analysis the subjects, study design and implementation. Original researchs published from 2010 to 2012 were also analysis the area of research. Results A total of 1 409 original articles were published from 2005 to 2012. Among them, 77.5% were the human study, mainly were case series (36.45%) and case-control studies (24.91%). The percentage of parallel control and self-control clinical studies increased from 8.42% to 11.08%. Eight-year longitudinal analysis found there was a significant difference in distribution of study design (H=90.39, P<0.001). However, The articals with Jadad score over 3 points were only 10.9% among parallel control clinical studies. The main areas of research were etiology and treatment from 2010 to 2012. Conclusions There are some changes in study design in original articals published in the Journal of Clinical Pediatrics, but the propotion of high quality evidence based researchs should be improved.%目的 评价《临床儿科杂志》所刊论著的研究设计类型、研究质量和研究领域.方法 手工检索并评阅和分析2005年至2012年《临床儿科杂志》所刊论著的研究对象、设计、方案实施,以及2010年至2012年所刊论著的研究领域.结果 2005至2012年共发表论著1 409篇,以人为研究对象的占77.5％；研究设计类型以病例分析为主,占36.45％；观察性病例对照研究占24.91％.近年来,平行对照和自身对照临床试验研究所占的比例有所增加,从8.42％增加到11.08％.8年来所刊论著的研究设计类型差异有统计学意义(H=90.39,P＜0.001).在平行对照临床试验研究中,Jadad评分在3分以上的仅占10.9％.2010至2012年所刊论著以探讨病因和治疗最为多见.结论 近年来《临床儿科杂志》所刊论著的研究设计类型有所变化,但高质量的循证医学研究所占比例仍有待提高.
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