Objective To measure the neurosensory retinal thickness at macular region in normal eyes using Optic Coherent Tomography. Methods Asteroid-shape scanning of the central retina using Copernicus SOCT was performed in 75 normal eyes. Each scan was 7 mm long, centered at fovea and move along 8 directions (temporal, superior-temporal, superior, superior-nasal, nasal, inferior-nasal,inferior, and inferior-temporal). Retinal thickness was sampled at50、150、500、 1000、1500 μm from fovea at each direction. There were total 3075 data points obtained. Results Average neuroepithelium thickness at macular region was (143.15 ± 13.57) μm in normal eyes. The thickness at 1000 m from fovea on temporal, superior, nasal, inferior, inferior-nasal, and inferior-temporal retina were statistically different for two ocular sides and for two genders. The neuroepithelium at 1000 μm from fovea on nasal retina was significantly thicker than on temporal retina. Conclusion OCT is an effective way to precisely measure macular retinal thickness in vivo. The data obtained from normal eyes in this study will provide valuable information for quantitative analysis of macular thickness in diseased eyes.%目的 应用相干光断层成像技术(OCT)测量正常眼黄斑区视网膜神经上皮层的厚度.方法 应用哥白尼Soct对75只正常眼进行经黄斑中心凹的星状扫描,扫描长度7mm,测量黄斑中心小凹,颞侧、颞上方、上方、鼻上方、鼻侧、鼻下方、下方、颞下方八个方向,分别距中心小凹距离50、150、500、1000、1500 μm的视网膜神经上皮的厚度,共计3075个数据,进行统计学计算和检验.结果 正常眼黄斑中心小凹的视网膜神经上皮厚度为(143.15 ±13.57) μm,正常眼黄斑区神经上皮厚度左右眼别之间,男女之间在1000μm处颞侧、上方、鼻侧、鼻下方、下方、颞下方的神经上皮厚度在统计学上有差异.中心小凹1000 μm外鼻侧视网膜神经上皮厚度大于颞侧神经上皮厚度.结论 OCT能够精确测量正常活体黄斑视网膜厚度,正常值的测定结果有利于对黄斑疾病的诊断治疗提供客观、定量分析.
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