近视眼患者近视程度对视网膜神经纤维层厚度的影响

摘要

目的：探讨不同近视程度对于其视网膜神经纤维层（ RNFL ）厚度的影响。方法选取我院自2014年9月至2015年9月间收治的120例近视患者作为实验对象，对每一位患者进行视力及屈光检测，然后根据测评结果将其分成3组，即低度近视40例，中度近视40例，高度近视40例，选取同期进行视力检测的健康人40例作为对照组，使用OCT对4组受检者的RNFL进行检测，分析不同近视程度对于RNFL厚度的影响。结果低度近视组患者的RNFL数据和对照组差异不具有统计学意义（ P＞0.05）；和其他两组数据对比差异显著（ P ＜0.05）。结论近视程度越高则患者的RNFL厚度逐渐降低。通过对RNFL厚度检测可判断患者的近视程度。%Objective To investigate the effect of different degrees of myopia on the thickness of retinal nerve fiber layer (RNFL).Methods From September 2014 to September 2015, totally 120 cases of myopia in our hospital were en-rolled in this study.Patients were divided into 3 groups according to the degree of myopia:mild ( n =40) , moderate ( n=40) and high myopia ( n =40).Another 40 normal subjects were included as control.Optical coherence tomography ( OCT) was used to measure RNFL thickness.Results RNFL thickness was not significantly different between mild myo-pia patients and normal subjects, whereas in patients with moderate to high myopia, RNFL was significantly reduced ( P<0.05).Conclusions RNFL thickness is significantly reduced in moderate to high degree of myopia.RNFL thickness can be used to aid in evaluation the degree of myopia.