MRI纹理分析在脑脓肿与胶质母细胞瘤鉴别诊断中的应用价值

摘要

Objective To explore the value of texture analysis of MRI image in differentiating between brain abscess and glioblastoma ( GBM).Methods All MRI data of 25 patients with brain abscess and 37 patients with GBM confirmed by surgery or pathology were analyzed retrospectively. The axial, sagittal, and coronal positions of the enhanced T 1 WI sequence were selected to show the largest level of the enhanced enhancement (the region of interest,ROI), and the texture features of the lesion were extracted by FireVoxel software.Results MRI findings of cystic necrosis of gland abscess wall and GBM were significantly different.The skewness and kurtosis parameters of the brain abscess group were higher than those of the GBM group , and there were significant differences between the two groups ( P ＜0.05 ).Conclusion Texture analysis can provide objective and quantifiable information characteristics , and has certain clinical value for the identification of brain abscess and GBM.%目的 探讨MRI纹理分析在鉴别脑脓肿与胶质母细胞瘤的应用价值.方法 回顾性分析徐州医科大学附属医院经临床或手术、病理证实的25例脑脓肿和37例胶质母细胞瘤患者的MRI资料.通过FireVoxel软件在MRI增强扫描T1 WI的轴位、矢状位及冠状位,选取明显强化部分范围最大层面(感兴趣区, ROI),提取病灶的纹理特征进行分析.结果 脑脓肿脓肿壁和胶质母细胞瘤囊变坏死的MRI表现有明显差异;脑脓肿组的偏度、峰度参数显著高于胶质母细胞瘤组,两者的差异有统计学意义(均P＜0.05).结论 纹理分析可以提供客观、可量化的信息特征,对脑脓肿与胶质母细胞瘤的鉴别有一定的临床价值.