首页> 中文期刊> 《实用临床医药杂志》 >肝癌术后抗乙型肝炎病毒治疗对预防肝癌复发的研究

肝癌术后抗乙型肝炎病毒治疗对预防肝癌复发的研究

         

摘要

Objective To investigate the anti - hepatitis B virus after liver surgery to prevent recurrence of liver cancer treatment effects and impact. Methods Twenty cases with hepatitis B virus replication in liver cancer liver cancer were randomly divided into two groups: control group (n = 10) for radical resection of hepatocellular carcinoma only; treatment group (n = 10) for liver cancer after radical resection of lamivudine antiviral therapy. Liver function, HBV DNA quantification, Child-pugh score and survival of the two groups were observed and compared. Results In the treatment group, the liver function improved more significantly than the control group (P < 0.01); 12 months later, the treatment group's quantitative HBV DNA levels and Child - pugh score were significantly lower than those in January and of the control group. There was significant difference ( P < 0.01 ). The average survival time of treated group was (23.4 ± 2.2) months, significantly higher than the control group (15.1 ± 2.1 ) months. The difference was statistically significant (P < 0.01 ). Conclusion The effect of anti - hepatitis B virus after liver surgery to prevent recurrence of liver cancer is obvious.%目的 探讨肝癌手术后抗乙型肝炎病毒(HBV)治疗对预防肝癌复发的效果及影响.方法 将20例并发乙型肝癌病毒复制的肝癌患者随机分为两组:对照组10例,单纯接受了肝癌根治术;治疗组10例,在肝癌根治术后应用拉米夫定进行抗病毒治疗.观察比较两组患者肝功能,HBV DNA定量,Child-pugh积分及生存率.结果 治疗组较对照组肝功能改善明显(P

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