ABSTRACT:Objective To explore the influence of comprehensive nursing intervention on nosocomial fungal infection in senile patients with COPD. Methods A total of 138 patients in 2013 were assigned in observation group and received comprehensive nursing intervention, and 141 COPD patients in 2012 were in the control group and they were given COPD routine nursing. Sec-ondary fungus infection and incidence rate were compared in the two groups. Results Infection sites of two groups were both located in respiratory tract, intestine and mouth. Secondary fungal in-fection in the intervention group were significantly lower than that in the control group, the differ-ence was statistically significant(P<0. 01). Conclusion Comprehensive nursing intervention could reduce the incidence of elderly patients with secondary fungus infection, so it has positive signifi-cance to control nosocomial infection.%目的：探讨综合护理干预对高龄慢阻肺患者院内真菌感染的影响。方法将2013年度本科收治的138例患者作为观察组，给予综合护理干预；将2012年度收治的141例慢阻肺患者作为对照组，给予慢阻肺常规护理，比较2组患者继发性真菌感染的部位、发生率。结果2组感染部位均以呼吸道、肠道、口腔为主，观察组继发性真菌感染发生率显著低于对照组，差异有统计学意义（P ＜0．01）。结论综合护理干预降低了高龄患者继发性真菌感染的发生率，对控制院内感染有积极意义。
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