黄芪建中汤联合中药穴位贴敷疗法治疗脾胃虚寒型慢性胃炎的疗效观察

摘要

Objective To explore the effect of huangqi jianzhong decoction combined with acupoint application of traditional Chinese medicine on the treatment of patients with chronic gastritis differentiated as asthenia cold of spleen and stomach.Methods Totally 130 patients with chronic gastritis differentiated as asthenia cold of spleen and stomach were selected and randomly divided into two groups,65 cases in each group.The control group was treated by huangqi jianzhong decoction,while the observation group was given huangqi jianzhong decoction combined with acupoint application of traditional Chinese medicine.The serum PG Ⅰ,PG Ⅱ,GS,TCM syndrome score and the effects were compared before and after treatment in both groups.Results After treatment,the scores of the two groups significantly reduced,and the score of the observation group was significantly lower than the control group (P ＜0.05).The total effective rate of TCM syndrome was 84.62％ in the control group,which was significantly lower than 96.92％ in the observation group (P ＜ 0.05).The total effective rate of gastroscopy was 75.38％ in the control group and 86.15％ in the observation group (P ＞ 0.05).The PG Ⅰ and GS were significantly higher in the observation group after treatment,and were significantly higher than those in the control group (P ＜ 0.05).Before and after treatment,there was no significant change in the level of PG Ⅱ between the two groups (P ＞ 0.05).Conclusion Huangqi jianzhong decoction combined with acupoint applicationof traditional Chinese medicine can effectively improve TCM syndromes of patients with chronic gastritis differentiated as asthenia cold of spleen and stomach,and regulate the expression of PG Ⅰ and GS.%目的 探讨黄芪建中汤联合中药穴位贴敷疗法治疗脾胃虚寒型慢性胃炎的疗效.方法 选择130例脾胃虚寒型慢性胃炎患者,随机分为对照组和观察组,每组65例.对照组给予黄芪建中汤治疗,观察组给予黄芪建中汤联合中药穴位贴敷治疗.比较治疗前后患者血清胃蛋白酶原Ⅰ(PCⅠ)、胃蛋白酶原Ⅱ(PGⅡ)、胃泌素(CS)、中医证候评分和治疗效果.结果 治疗后,2组评分均明显降低,且观察组评分显著低于对照组(P＜0.05);对照组中医证候总有效率为84.62％,显著低于观察组的96.92％ (P＜0.05);对照组胃镜总有效率为75.38％,与观察组的86.15％无显著差异(P＞0.05);观察组PCⅠ、GS均显著升高,且显著高于对照组(P＜0.05).治疗前后,2组PGⅡ水平均无显著变化(P＞0.05).结论 黄芪建中汤联合中药穴位贴敷治疗脾胃虚寒型慢性胃炎,能够显著改善患者中医证候,调节PGⅠ和GS的表达.