利巴韦林联合血必净治疗重症肾综合征出血热31例临床分析

摘要

Objective To explore the clinical effect of ribavirin combined with xuebijing on the treatment of patients with severe hemorrhagic fever with renal syndrome (HFRS).Methods Totally 61 patients with HFRS were randomly divided into two groups.The treatment group was treated with ribavirin and xuebijing,while the control group was treated with ribavirin.Results The descent speed of serum procalcitonin in the treatment group was significantly higher than the control group (P ＜ 0.05).The recovery time of platelet,the recovery time of serum creatinine,the time of Hypotension shock,oliguria time and polyuria time in the treatment group were significantly shorter than the control group (P ＜ 0.05).Conclusion The clinical efficacy of ribavirin combined with xuebijing is better than single application of ribavirin in the treatment of patients with HFRS.%目的 探讨利巴韦林联合血必净治疗重症肾综合征出血热(HFRS)的临床疗效.方法 61例HFRS重症患者随机分为2组,治疗组采取利巴韦林联合血必净治疗,对照组采取利巴韦林治疗.结果 治疗组血清降钙素原下降速度显著高于对照组(P＜0.05).治疗组血小板复常时间、血肌酐复常时间、低血压休克时间、少尿时间、多尿时间显著短于对照组(P＜0.05).结论 利巴韦林联合血必净治疗HFRS的临床疗效优于单用利巴韦林.