首页> 中文期刊> 《临床和实验医学杂志》 >复发性高脂血症性急性胰腺炎临床特点分析

复发性高脂血症性急性胰腺炎临床特点分析

         

摘要

目的 探讨复发性高脂血症性急性胰腺炎(HLAP)患者的临床特点.方法 采用回顾性研究的方法,选取2010年1月至2018年1月首都医科大学附属北京天坛医院收治的33例复发性HLAP患者(HLAP组)和56例复发性非HLAP患者(NHLAP组),比较两组患者入院时的一般情况、体重指数、甘油三酯、C反应蛋白、血糖、住院时间、病情严重程度等指标.结果 HLAP组患者C反应蛋白、血糖、甘油三酯、体重指数(138.35±15.78 mg/L,9.01±3.19mmol/L,9.89±6.56 mmol/L,30.12±5.21 kg/m2)均高于NHLAP组(97.23±19.89 mg/L,6.15±1.21 mmol/L,2.28±1.31 mmol/L,24.56±5.31 kg/m2),差异均有统计学意义(P <0.05);HLAP组患者糖尿病比率、住院时间、并发症发生率及死亡率(36.4%,14.4±4.7 d,34.4%,9.4%)均高于NHLAP组(10.7%,9.8±3.5 d,10.7%,1.8%),差异均有统计学意义(P <0.05).结论 与复发性非高脂血症急性胰腺炎比较,复发性高脂血症性急性胰腺炎甘油三酯、血糖、体重指数、糖尿病所占比率明显升高,并且具有较高的并发症发生率及死亡率.%Objective To explore the clinical characteristics of recurrent hyperlipidemic acute pancreatitis. Methods 33 patients with recurrent HLAP (HLAP group) and 56 patients with recurrent non-HLAP (NHLAP group) admitted in this hospital during January 2010 to January2018 were selected by means of retrospective study. Results The blood levels of C-reaction protein, glucose, triglyceride and BMI in paiients of HLAP group were all higher than those of patients in NHLAP group (138. 35 ± 15. 78 mg/L, 9. 01 ± 3. 19 mmol/L, 9. 89 ± 6. 56 mmol/L, 30. 12 ±5. 21 kg/m2 vs. 97. 23 ± 19. 89 mg/L, 6. 15 ± 1. 21 mmol/L, 2. 28 ± 1. 31 mmol/L, 24. 56 ± 5. 31 kg/m2), showing statistical difference (P <0.05). The incidence of diabetes, mortality, complcations and hospital stays in HLAP group were higher than those of NHLAP group (36. 4%, 9. 4%, 34. 4%, 14. 4 ± 4. 7 d vs. 10. 7%, 1. 8%, 10. 7%, 9. 8 ± 3. 5 d) with significant statistical difference (P < 0. 05). Conclusion In comparison with recurrent non-hyperlipidemia acute pancreatitis, blood levels of triglycerides and glucose, body mass index, higher proportion of diabetes, in recurrent hyperlipidemia pancreatitia are significantly increased, and it has higher incidence of complications and mortality.

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