目的：评价针刺治疗不安腿综合征的临床疗效。方法：计算机检索EMbase、MEDLINE、中国知网、万方数据库、维普数据库及中国生物医学文献数据库，检索时间截止至2010年8月。同时手工检索天津中医药大学图书馆相关会议论文集及过期刊物。纳入所有针刺治疗不安腿综合征的随机和半随机对照试验。各评价者独立提取文献并进行研究质量评价。采用RevMan4.2.10软件进行统计学分析及失安全数分析；用漏斗图分析发表性偏倚。结果：纳入8篇随机对照试验，均为低质量研究。Meta分析，有效率：针刺组优于西药组(OR=13.87，95％CI[8.03，23.96 ])。失安全数分析显示评价结果较为稳定；漏斗图图形不对称，考虑存在发表性偏倚。结论：针刺治疗不安腿综合征具有一定疗效，但尚需开展大样本、高质量的随机双盲对照试验来进一步证实。%Objective: To assess the therapeutic effect of acupuncture for restless legs syndrome. Methods: The paper searched Embase,MEDUNE, CNKI CBM, WANFANG,VIP, Database, and handsearched relevant journals and conference proceedings. It included all randomized controlled trials ( RCTs) and quasi - RCTs of acu-puncture treatment for patients with restless legs syndrome. Datawere extracted and evaluated by two reviewers independently with a specially designed extraction form. The Cochrane Collaborations RevMan4.2.10 software was used for data analysis. At the same time, we do Fail - safe number analysis and use Funnel plot for the possible existence of publication bias. Results: A total of 8 trials involving 581 patients were included. Meta - a-nalysis showed that the total effective rate in the treatment group was better than that in the control group: Acupuncture group versus western medicine group (OR = 13. 87,95% CI [ 8.03,23. 96 ] ). Fail - safe number a-nalysis revealed a relatively stable result. Funnelplot is asymmetrica, which showed the possible existence of publication bias. Conclusion: Acupuncture is better, but further large - scale trials are required to define the role of acupuncture in the treatment of restless legs syndrome.
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