AS-OCT、Lenstar、UBM测量中央角膜厚度的结果比较

摘要

目的 比较前段光学相干断层扫描仪(AS-OCT)、Lenstar、超声生物显微镜(UBM)测量中央角膜厚度(CCT)的差异性、相关性、一致性.方法 采用横断面研究,纳入2015年10月到2016年8月于中国医科大学附属第四医院就诊的患者54例(83眼),按顺序行Lenstar、AS-OCT、UBM检查,测量CCT.差异性采用随机区组方差分析,相关性采用Pearson相关分析,一致性采用 Bland-Altman分析.结果 3种仪器的CCT测量结果有明显差异(P < 0. 05),两两比较差异有统计学意义(均P < 0. 05),3种仪器的 CCT测量结果有显著相关性(均P < 0. 001)和良好的一致性.结论 AS-OCT、Lenstar、UBM的CCT测量结果有良好一致性和高度相关性,在某些情况下可以相互替代.AS-OCT可作为青光眼早期筛查、判断CCT厚度的首选.%Objective To compare the differences,correlation,and consistency among central corneal thickness (CCT) measurements by anterior segment optical coherence tomography (AS-OCT),Lenstar,and ultrasound biomicroscopy (UBM). Methods In this cross-sectional study,AS-OCT,Lenstar,and UBM were used to measure the CCT in 54 patients (83 eyes) between October 2015 and August 2016 in the Fourth Affiliated Hospital of China Medical University. Data were statistically analyzed by random analysis of variance, Pearson correlative analysis,and Bland-Altman analysis to compare the difference,correlation,and consistency among the three instruments. Results The differences in the mean CCT measured by the three instruments were statistically significant (P < 0. 05 for all comparisons). There was also a high correlation (all P < 0. 001) and consistency among the three instruments. Conclusion There is a high level of correlation and consistency in the CCT measurements by the three instruments. Therefore,these could be interchangeable under some circumstances. AS-OCT could be the first choice as an early screening tool for glaucoma.