孕早期胎盘体积和血管指数对小于胎龄儿的预测

摘要

Objective:To evaluate the ability of first-trimester placental volume and vascular indices to predict small-for-gestational-age(SGA) birth weight pregnancies.Methods:Retrospective comparative analysis placental volume,multiples of median(MOM),Doppler vascular index in 242 single pregnancy at 11～13 weeks+6 without complications,fetal malformations in our hospital between appropriate-for-gestational-age (AGA) and SGA at delivery.Results:The placental volume and MOM in the SGA group were significantly lower than those in the AGA group (AGA 74.32±20.28,SGA 51.57±11.65,P=0.008;AGA 1.00:±0.05,SGA 0.93±0.04,P=0.004).There were no significant differences in vascular indices,including vascularization index (VI),blood flow index(FI) and vascularized blood flow index(VFI)(VI:P=0.602,FI:P=0.561,VFI:P=0.490).Conclusions:The placenta volume measured by tlree-dimensional ultrasonography in 11～13 weeks+6 can predict SGA,while the vascular indices have little effect on SGA.%目的:评估孕早期胎盘体积和血管指数预测小于胎龄儿(SGA)能力.方法:回顾性对比分析242例11～13周+6在我院就诊且随访至胎儿足月出生的无合并症、胎儿畸形单胎妊娠适于胎龄儿(AGA)与SGA胎盘体积、胎盘体积中位倍数值(MOM)、多普勒血管指数.结果:孕早期SGA组胎盘体积、胎盘体积MOM显著低于AGA组(AGA 74.32±20.28,SGA 51.57±11.65,P=0.008;AGA 1.00±0.05,SGA0.93±0.04,P=0.004).两组血管指数,包括血管化指数(VI),血流指数(FI)和血管化血流指数(VFI)均无显著差异(VI:P=0.602,FI:P=0.561,VFI:P=0.490).结论:孕早期三维超声测量的胎盘体积可以预测SGA,而三维能量多普勒血管指数对SGA预测作用不大.