The extant literature lacks collabarative research on determinants of knowledge acquisition and integration ability of culture creativity enterprise, that is, studying at the same time from three aspects of environment, supply chain coordination relationship and integration. Hypotheses on the determinants from these three aspects are therefore proposed and tested through 540 valid questionnaires. Results of stepwise regression analyses show that knowledge acquisition ability is positively affected by interpersonal relationship, followed by commitment, innovation atmosphere, enterprise internal and external supply chain integration, but is not remarkably affected by external supporting environment and trust. Knowledge integration ability positively and significantly by trust, followed by commitment, enterprise external supply chain integration, interpersonal relationships and external supporting environment, but is not remarkably affected by enterprise innovation atmosphere and internal supply chain integration. Analysis of such differences indicates that both knowledge acquisition and integration capability are not related with the scale of the enterprise, but are significantly associated with age and type of business. And further testing on age and type of business reveals that in order to enhance knowledge acquisition and integration capabilities, one should take contingency perspective to take according measures.%现有文献欠缺从环境、供应链协调关系和供应链整合三方面同时研究文化创意企业知识获取和整合能力的影响因素及相对重要度。从这三方面构建了两种能力影响因素的假设，基于540份有效问卷检验了假设。全部样本逐步回归分析表明，知识获取能力主要受人际关系的正影响，其次受承诺、企业创新氛围、企业内部和外部供应链整合的正影响，外部支持环境和信任的影响不显著；知识整合能力主要受信任的正影响，其次受承诺、企业外部供应链整合、人际关系和外部支持环境的正影响，企业创新氛围和内部供应链整合的影响不显著。差异性分析表明，知识获取和整合能力都与企业规模无关，但都与企业成立年限和业务类型显著相关。依据成立年限和业务类型的样本分组假设检验表明，为提升知识获取和整合能力，需运用权变观点采取措施。
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