SEPS1——新发现的炎症相关基因

摘要

Selenoprotein S1 (SEPS1) , a novel gene involved in the stress response of endoplasmic reticulum and inflammation control. Recent results provide a direct mechanistic link between SEPS1 and the production of inflammatory cytokines, suggesting SEPS1 may play a major role in the mediation of inflammation in IDDM and some other immunological disorders.%Selenoprotein S1(SEPS1),一种新发现的对内质网的应激反应和炎症控制起作用的基因.近来的研究结果显示SEPS1与炎症细胞因子的产生存在直接的联系,可能在炎症介导的IDDM以及一些其他的免疫异常中起主要作用.