网络成瘾大学生脑功能性磁共振成像特点

摘要

目的:利用任务背景刺激功能性磁共振成像（functional magnetic resonance imaging,fMRI）,探讨网络成瘾(internet addiction,IA)大学生的脑功能特点.方法:以网络游戏内容作为实验刺激任务,采用组块设计方法,对19名IA大学生及19名正常对照受试者进行脑部fMRI.对2组受试者脑功能分别予以组内和组间分析,得出2组受试者在观看网络游戏录像时平均脑功能激活图,并分析比较2组脑区激活的差异.结果:19例IA者及19例正常对照受试者,网络游戏任务刺激后脑区均显著激活,IA组较正常对照受试者激活增强的脑区有右侧顶上小叶、右侧颞叶脑岛、右侧顶叶楔前叶、右侧扣带回和右侧颞上回.结论:网络游戏任务刺激均引起正常人及IA者视空注意及执行中枢的激活；IA者存在脑功能异常和右侧大脑偏侧化激活现象.%Objective To explore the functional locations of brain regions related to internet addiction (IA) with task-functional magnetic resonance imaging (fMRI). Methods Nineteen college students who had internet game addition and 19 controls accepted the stimuli of videos via computer. The 3.0 Tesla MRI was used to record the results of echo plannar imaging. The block design method was used. Intragroup and intergroup analysis results in the 2 groups were obtained. The differences between the 2 groups were analyzed. Results The internet game videos markedly activated the brain regions of the college students who had or had no internet game addiction. Compared with the control group, the IA group showed increased activation in the right superior parietal lobule , right insular lobe, right precuneus, right cingulated gyms, and right superior temporal gyrus. Conclusion Internet game tasks can activate the vision, space, attention and execution center which are composed of temporal occipital gyrus and frontal parietal gyrus. Abnormal brain function and lateral activation of the right brain may exist in IA.