目的:创新使用臭氧水和臭氧油外用治疗婴幼儿特应性皮炎,观察其临床疗效和安全性.方法:将60例婴幼儿特应性皮炎患者分为治疗组和对照组,治疗组用臭氧水洗浴每周3～5次,每次15 min,臭氧油外用每日2次,对照组用温水洗浴、基础油外用,疗程2周,两组患者必要时加用保湿霜,观察疗效和不良反应.结果:外用臭氧治疗婴幼儿特应性皮炎3～5 d后可见患儿皮损渗出减少、糜烂愈合.外用臭氧治疗组和对照组l周有效率分别为80.0％和20.0％,2周有效率分别为89.6％和30.7％,两组疗效比较差异有统计学意义(P＜0.001).两组患者在治疗过程中均未出现明显不良反应.结论:外用臭氧治疗婴幼儿特应性皮炎安全、有效,值得在临床推广应用.%Objective:To evaluate the clinical efficacy and safety of the innovative topical ozone therapy for infantile atopic dermatitis.Methods:Sixty children with atopic dermatitis were divided into a treatment group and a control group.The treatment group was showered with ozonated water (3-5 times a week) and smeared with ozonated oil (twice a day),while the control group was washed with warm running water and smeared with base oil,adding moisturizer if necessary.The treatment course was 2 weeks.Efficacy and side effect were evaluated.Results:The skin exudation was reduced and erosion was healing after 3-5 days topical ozone therapy for infantile atopic dermatitis.The effective rates were 80.0％ and 20.0％ in the treatment group and control group for 1 week,and 89.6％ and 30.7％ for 2 weeks,respectively,with significant difference between the 2 groups (P＜0.001).Conclusion:Innovative treatment of infantile atopic dermatitis with topical ozone application is safe and effective,which is worth popularizing in clinic.
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