喉癌幸存者睡眠质量与生命质量相关性分析

摘要

[ Abstract] Objective: To investigate the sleep quality and the quality of life (QOL) of laryngeal cancer survivors, and to explore the correlation between sleep quality and QOL in laryngeal cancer survivors, to provide basis for improving the sleep quality and the QOL of laryngeal cancer survivors. Methods: In total, 316 laryngeal cancer survivors treated by surgical treatment and pathologically confirmed in our department from January 2014 to December 2017 were selected as research ob-jects. A self-made questionnaire was used to investigate the general data of the patients and the history of diseases. The sleep quality was evaluated by the Pittsburgh sleep quality index scale (PSQI), and the QOL of the patients was evaluated by the European Organization for Research and Treatment of Cancer (EORTC) QLQ-C30 (hereinafter referred to as "QLQ-C30"). Results: The total score of the sleep quality of laryngeal cancer survivors was 6~18, with an average of 10. 39 ± 6. 62, and 210 ( 66. 46% ) patients had poor sleep quality, namely, sleep disorders ( PSQI > 8 ). The overall QOL score was 81. 56 ± 34. 08. According to the scores indicating different functions, functions from high to low were role function, cognitive function, emotional function, body function and social function. The 5 leading symptoms were anhelation, economic difficulties, insomnia, loss of appetite and pain. Pearson corre-lation analysis showed that the total score of sleep quality in larynx survivors was positively correlated with body function, role function, cognitive function, emotional function, social function, fatigue, anhelation and insomnia (P<0. 05). Conclu-sion: Sleep disorders are common among laryngeal cancer survivors, and sleep quality is closely related to QOL. Therefore, effective measures should be taken to improve sleep quality and the QOL.%目的:了解喉癌幸存者睡眠质量与生命质量现状,并探讨两者的相关关系,为改善患者睡眠质量、提高生命质量相关依据.方法:选取遂宁市中心医院耳鼻咽喉科2014年1月至2017年12月收治的经手术治疗且术后病理确诊的316例喉癌幸存者作为研究对象,采用自制的肿瘤调查问卷对患者的一般资料、既往疾病史等进行调查,采用匹兹堡睡眠质量(the pittsburgh sleep quality index,PSQI)量表评价患者的睡眠质量,采用欧洲癌症研究与治疗组织(European Organization for Research and Treatmen of Canncer,EORTC)生命质量核心量表( quality of life questionnaire, QLQ-C30)评价患者的生命质量.结果:喉癌幸存者睡眠质量总分6 ~18 分,平均(10. 39 ± 6. 62)分,有210 例(66. 46% )患者睡眠质量差即存在睡眠障碍(PSQI≥8分).喉癌幸存者QLQ-C30评价总体健康状况／生命质量评分为(81. 56 ± 34. 08)分.功能领域得分由高到低依次为:角色功能、认知功能、情绪功能、躯体功能和社会功能;症状领域得分前5位依次为:气促、经济困难、失眠、食欲丧失和疼痛. Pearson相关性分析显示,喉癌幸存者睡眠质量总分与生命质量的躯体功能、角色功能、认知功能、情绪功能、社会功能以及疲劳症状、气促症状、失眠症状得分呈正相关关系(P<0. 05).结论:TOMO计划系统中喉癌幸存者普遍存在睡眠障碍,且睡眠质量与生存质量密切相关.因此应采取有效措施改善患者睡眠质量、提高生命质量.