偏侧空间忽略的注意障碍-ERP一例

摘要

目的 探讨偏侧空间忽略(HSN)患者的注意成分变化.方法 记录1例HSN患者在执行提示—靶的实验范式时的脑电变化及反应时,进而探讨其行为学特点,及不同注意相关的事件相关诱发电位(ERP)成分变化.结果 与右侧靶目标相比,患者对左侧靶目标的反应时明显延长;提示类型及靶出现的侧别均对5个ERP成分(antN1,postN1,LPD,P1,P2)的波幅和潜伏期影响的主效应不显著.与右侧半球相比,左侧半球的P2及postN1成分体现的提示类型的半球偏侧化效应更显著.结论 左侧HSN患者在基于空间和物体的注意选择时表现出显著的左侧半球的偏侧化效应.%Objective To investigate the changes of attentional compositions of subjects with hemispatial neglect(HSN).Method The electrical activities of the brain and respond time were recorded when one subject with HSN was carrying out the cue-target experimental paradigm. The attention related ERP (event-related potentials) components and behaviors data were analyzed.Results The respond time to the targets located in the left side was longer than ones in the right side; the main effect of cue types or the sides of targets was unremarkable to the amplitudes and lantency of 5 attention related ERP components ( antN1, postN1, LPD, P1, P2) . The P2 and post N1 in the left hemisphere indicated more obviously lateralization than in the right hemisphere.Conclusion Subjects with HSN show up lateralization in the left hemisphere when paying space-based or object-based attention.