联合监测 C-反应蛋白与降钙素原在急性胰腺炎诊治中的意义

摘要

Objetcive To investigate the clinical value of C-reactive protein(CRP) and calcitonin original levels in clinical treatment of acute pancreatitis patients .Methods Seventy patients with acute pancreatitis were retrospectively analyzed .All the cases were randomly divided into two groups.Observation group( n =35) complicated with infection and control group ( n =35) without in-fection.The CRP and procalcitonin levels of the two groups were monitored and the clinical indicators ,complication ratio,mortality rate of two groups were collected and analyzed .Results The white blood cell counts , the CRP and procalcitonin levels of observation group was higher than that of the control group ( P <0.01).Shock, DIC, complication ratio and mortality rate of observation group were higher than that of control group ( P <0.05 or P <0.01 ).The CRP and procalcitonin levels approached or reached the level of infec -tion.Conclusion Monitoring the levels of CRP and calcitonin original levels in acute pancreatitis patients have important clinical value for the judgment of infection and improvement of the therapeutic efficacy and prognosis .%目的：探讨联合监测C-反应蛋白（ C-reactive protein，CRP）与降钙素原水平在急性胰腺炎临床诊治中的价值与意义。方法回顾性分析70例急性胰腺炎患者的临床资料，35例合并感染者为观察组，35例无感染者为对照组。联合监测两组患者CRP及降钙素原水平，比较两组患者临床指标、并发症发生率、病死率等。结果观察组白细胞总数、CRP和降钙素原水平三项指标均高于对照组（ P ＜0．01）。观察组休克、弥散性血管内凝血（DIC）发生率和病死率均高于对照组（ P ＜0．05或P ＜0．01）。观察组CRP及降钙素原均超过感染水平。结论联合监测急性胰腺炎患者CRP与降钙素原水平，能够有效对患者感染情况做出诊断，从而提高治疗效果，对于急性胰腺炎的临床诊治具有重要意义。