50Hz磁场照射对小鼠嗅觉辨别能力的影响

摘要

Objective: To investigate whether chronic exposure to extremely low frequency magnetic field ( ELF-MF) (50 Hz) can influence olfactory discrimination in mice. Methods: A habituation-dishabituation pattern was used to study olfatory discrimination in mice following exposure to 50 Hz magnetic field of 1 mT(1 hour/day) for 20 days. The motor behavior(locomotion) and exploring behavior were detected by open field test. Results: After exposure to 50 Hz magnetic field of 1 mT( 1 hour/day) for 20 days,there were no significant differences about motor behavior(locomotion) , exploring behavior and olfactory discrimination in mice. Conclusions: Exposure to chronic ELF-MF has no effect on olfactory discrimination in mice.%目的:探讨长期磁场暴露对成年小鼠嗅觉辨别功能的影响.方法:采用习惯化-去习惯化模型,连续20 d每天1 h的1 mT、50 Hz磁场照射小鼠,观察对小鼠嗅觉辨别功能的影响.采用旷场行为检测小鼠的活动量和探究行为.结果:连续20 d每天1 h的1 mT、50 Hz磁场照射后,小鼠的运动能力、探究能力及嗅觉辨别功能没有显著性变化.结论:连续20 d每天1 h的1 mT、50 Hz磁场照射不影响嗅觉辨别能力.