脑干海绵状血管瘤显微外科手术治疗的有效性及其预后

摘要

目的:探讨显微外科手术对脑干海绵状血管瘤病人的有效性及其预后.方法:选取12例脑干海绵状血管瘤病人作为研究对象,严密观察病人术后临床症状的缓解情况,同时采用欧洲癌症研究及治疗组织生活质量核心量表对比病人在术前、术后的生活质量变化情况.结果:术后病人头痛、呕吐、共济失调的发生率均较术前降低(P<0.05);脑干海绵状血管瘤病人术前和术后3个月、6个月和12个月的生活质量总分及其各维度得分间差异均有统计不意义(P<0.05~P<0.01),且术后3个月、6个月和12个月的生活质量得分均高于术前(P<0.05).结论:显微外科手术治疗脑干海绵状血管瘤具有良好的疗效,有利于改善病人的预后,提高病人术后的生活质量.%Objective:To investigate the effectiveness and prognosis of microsurgery in the treatment of cavernous angiomas in brain stem.Methods:The remission of clinical symptoms in 12 patients with cavernous hemangioma were observed after operation.The quality of life in all cases between before and after operation was compared using the European cancer research and treatment group scale. Results:The incidence rates of headache,vomiting and ataxia in all patients reduced after operation(P<0.05).The total score of life quality and each dimension score in all patients between before operation,after 3,6 and 12 months of operation were different,and the scores of life quality after 3,6 and 12 months of operation were higher than that of before operation(P<0.05).Conclusions:The effect of microsurgical treatment of cavernous hemangioma in brain stem is good,which can improve the prognosis and the quality of life of patients after operation.