中波高能紫外线联合他克莫司软膏治疗白癜风临床疗效分析

摘要

Objective :To analyze the clinical curative effect of MW high -energy ultraviolet combined with tacrolimus ointment on vit‐iligo and its feasibility .Methods:80 cases of vitiligo hospitalized by our hospital from June 2012 to June 2013 were randomly divided into the control group and the observation group .The control group was treated with tacrolimus ointment while the observation group was treated with MW high -energy ultraviolet combined with tacrolimus ointment ,the clinical curative effect observed and compared .Result:The total effective rate of the control group was 80 % ,which was significantly higher than that of the control group (45 % ) ,the differ‐ence between the two groups being significant(χ2=6 .23 ,P < 0 .05) .The average time for the 40 patients in the observation group to repigment is (1 .45 + 0 .76) months and that in the control group is (1 .86 + 0 .84) months ,the difference between the two groups being significant ( P <0 .05);there was no significant difference between the two groups in terms of the adverse reaction rate ( P > 0 .05) . Conclusion:MW high -energy ultraviolet combined with tacrolimus ointment has a significant clinical effect on vitiligo ,which is safe and feasible and worth promoting clinically .%目的：分析中波高能紫外线联合他克莫司软膏治疗白癜风临床可行性及疗效。方法：将2012年6月至2013年6月的60例白癜风患者随机分为对照组和观察组，对照组患者采用他克莫司软膏外用，观察组患者进行中波高能紫外线联合他克莫司软膏治疗，观察并比较两组治疗效果。结果：观察组患者治疗的有效率为80．0％，明显高于对照组的45．0％，两组比较，差异有统计学意义（χ2＝6．23， P ＜0．05）；观察组40例患者平均皮损复色时间为（1．45 ± 0．76）月，而对照组40例患者平均皮损复色时间为（1．86 ± 0．84）月，两组比较，差异有统计学意义（P ＜0．05）；两组患者不良反应的发生率比较，差异无统计学意义（P ＞0．05）。结论：中波高能紫外线联合他克莫司软膏治疗白癜风，临床效果显著，安全性和可行性高，值得临床推广使用。