支原体感染与儿童支气管哮喘关系研究进展

摘要

支气管哮喘是儿童时期最常见的慢性疾病，主要以气道慢性炎症为特点。支原体感染后诱发哮喘及哮喘持续不缓解并导致哮喘迅速恶化的病人越来越多，导致这一现象的主要原因有气道直接损伤（物理损伤、毒性因子损伤）、免疫失衡、遗传相似性。%The bronchial asthma is the most common chronic diseases in childhood , mainly characterized by chronic inflammation of the airway . It is more and more common that asthma induced by mycoplasma infection continues without any sign of mitigation , resulting in the rapid deteriora-tion of asthma.Causes of the disease falls into three major categories:direct injury to the airway (physical injury and toxic factors injury), immune imbalance and the genetic similarities .